University of Pavia, Italy Endocrine-Nutritional Service

This study was conducted on 49 patients of fertile age, suffering from Iron Deficiency
Study objective:

to demonstrate that the use of Captafer is a valid alternative to oral treatment wich are commonly used in cases of iron deficiency, and wich are often poorly tolerated by patients.

 

After 1 month: serum iron +78%

Subjects with serum iron level <60 µg/dl

After 2 months: Serum ferritin +80%

Subjects with a ferritin level <20 ng/ml

UNIVERSITY OF BOLOGNA, ITALY ST ORSOLA HOSPITAL

This study was carried out on 25 patients suffering from IBD (Crohn's disease and UIcerative Colities).
Study objective:

to assess the role of captafer in cases of iron deficiency and chronic anemia, which commonly occur in patients suffering from IBD.

After 2 months

Serum Iron increased by 70%

After 2 month

Serum Ferritin increased by 70%

After 4 months

a significant increase in hemoglobin

FOLIC ACID clinical trials:

Folic acid supplements before conception and in early pregnancy (up to 12 weeks) for the prevention of birth defects

This review of five trials, involving 7391 pregnancies (2033 with a history of a pregnancy affected by a NTD and 5358 with no history of NTDs), shows the protective effect of daily folic acid supplementation in doses ranging from 0.36 mg (360 µg) to 4 mg (4000 µg) a day, with and without other vitamins and minerals, before conception and up to 12 weeks of pregnancy, for preventing the recurrence of these defects.

CONCLUSIONS:
Folic acid, alone or in combination with vitamins and minerals, prevents NTDs, but does not have a clear effect on other birth defects.